Expired Study
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Cedar Knolls, New Jersey 07927


The objective of this study was to evaluate the anti-plaque efficacy of the Anacor prototype dentrifice as compared to commercial control products following a single use of the dentrifice.

Study summary:

The widespread successful use of triclosan as an anti-inflammatory and anti-bacterial agent is well documented. The standard dentrifice has demonstrated a robust anti-plaque and anti-inflammatory effect providing multiple benefits. There is a clear value to identify additional agents with the same dual action with a comparable or an enhanced level of efficacy. This study examined the anti-plaque efficacy following a single use of the prototype dentifrice.


Inclusion Criteria: - Must be between ages 18 to 65 years inclusive - Have a minimum of 16 natural uncrowned teeth (excluding 3rd molars) present - Must give written informed consent - Be in good general health - Must discontinue oral hygiene for 24-hours after initial appointment - No known history of allergy to personal care/consumer products or their ingredients, relevant to any ingredient in the test products as determined by the dental/medical professional monitoring the study Exclusion Criteria: - Medical condition which requires pre-medication prior to dental visits/procedures - Advanced periodontal disease - 5 or more decayed, untreated dental sites - Diseases of the soft or hard oral tissues - Orthodontic appliances - Abnormal salivary function - Use of drugs that can affect salivary flow - Use of antibiotics one (1) month prior to or during this study - Use of any over the counter medications other than analgesics (i.e. aspirin, ibuprofen, acetaminophen, naproxen), unless approved by the study medical staff - Pregnant or breastfeeding - Participation in another clinical study in the month preceding this study - Allergic to common dentifrice ingredients - Immune compromised individuals (HIV, AIDS, immuno suppressive drug therapy) - History of allergic reaction to any anti-inflammatory agents



Primary Contact:

Study Director
Pfizer CT.gov Call Center

Backup Contact:


Location Contact:

Cedar Knolls, New Jersey 07927
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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