Expired Study
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Portland, Oregon 97201


The purpose of this study is to see if a dietary supplement, R-alpha lipoic acid, is able to reduce risk factors in people with documented heart disease and increased levels of inflammation.


Inclusion Criteria: - Documented congestive heart disease (CHD)(defined as at least one significant coronary stenosis > 50% on angiography, or history of documented myocardial infarction) - Not diagnosed with unstable angina, uncontrolled hypertension, heart failure, recent myocardial infarction (within last six months) - Not taking insulin or oral hypoglycemic agents, anti-inflammatory drugs other than aspirin, or hormone replacement therapy - On stable doses for four weeks prior to entry of lipid-lowering therapy (statins), aspirin, and angiotensin-converting enzyme inhibitors or other blood pressure medications. P - No tobacco use within 3 months of the study - No laboratory evidence of renal, hepatic, or hematological abnormalities - Not currently taking vitamin or antioxidant supplements, including R-alpha lipoic acid, except standard multivitamin/mineral supplements containing not more than the Daily Value (DV) of the vitamins and minerals; - Elevated levels of urinary and plasma F2-isoprostanes - Elevated plasma levels of hs-CRP



Primary Contact:

Principal Investigator
Gerd Bobe, PhD
Oregon State University

Backup Contact:


Location Contact:

Portland, Oregon 97201
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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