Expired Study
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Boston, Massachusetts 02114


This is a pilot study to evaluate the findings of the Reflectance Confocal Microscopy when performed in cutaneous pigmentary disorders, such as vitiligo, melasma, post-inflammatory hyper-pigmentation and hypo-pigmentation. Confocal Microscopy is a recent diagnostic technique that has been used for observation of skin conditions that affect the superficial layers of the skin.


Inclusion Criteria: 1. Subjects 20-70 years of age. 2. Clinical diagnosis of vitiligo, melasma, post-inflammatory hypo or depigmentation or post-inflammatory hyperpigmentation. 3. Willing and able to understand and sign informed consent. 4. Able to complete study and comply with study procedures. Exclusion Criteria: 1. Use of topical therapies such as corticosteroids, protopic, hydroquinone and azelaic acid within the past 2 months. 2. Use of light therapy such as narrow-band-UVB, PUVA or laser within the past 2 months. 3. Intake of medications that can cause pigmentary changes within the past year. Examples are: - Antimalarials (chloroquine, hydroxychloroquine) - Chemotherapeutics (bleomycin, busulfan, doxorubicin, daunorubicin, fluorouracil, cyclophosphamide, and carmustine) - Heavy metals (gold, silver, bismuth, and mercury) - Tetracyclines (including minocycline, doxycycline) - Amiodarone - Azidothymidine - Clofazimine 4. Clinically significant abnormal findings or conditions (other than the pigmentary disorder), which might, in the opinion of the Principal Investigator, interfere with study evaluations or pose a risk to subject safety during the study. 5. Subjects who are known to be pregnant or planning a pregnancy.



Primary Contact:

Principal Investigator
Ernesto Gonzalez, MD
Massachusetts General Hospital

Backup Contact:


Location Contact:

Boston, Massachusetts 02114
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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