Indianapolis, Indiana 46202


Purpose:

The overall aim of this research is to utilize wound derived inflammatory cells from diabetic versus non diabetic human chronic wounds to understand mechanisms that are responsible for disregulated inflammation in individuals with diabetes. Biology of normal (peripheral blood derived cells) versus wound derived cells will also be studied.


Study summary:

Specific aims: 1. To study biology of wound derived inflammatory cells and fluid from diabetic versus non diabetic wounds. 2. To characterize mechanisms that are responsible for dysregulated wound inflammatory cell function in individuals with diabetes. 3. To characterize differences in the biology of normal peripheral blood derived cells versus wound derived cells. The long-term goal of this study is to determine the molecular mechanisms underlying impaired wound healing in diabetics.


Criteria:

Inclusion Criteria: - Ages 21-80 - Chronic Wound (present >4 weeks) - Diabetic & Non-diabetic - Adult surgical wounds Exclusion Criteria: - Inability to consent - Pregnant women - Therapeutically immunocompromised - Individuals defined in 45 CFR 46 Subparts B,C, and D, nor from any other population considered vulnerable 2.9


NCT ID:

NCT00777712


Primary Contact:

Principal Investigator
Sashwati Roy, Ph.D.
Indiana University

Jennifer Mohnacky, RDN
Phone: 317-278-2715
Email: jmohnack@iu.edu


Backup Contact:

Email: tjgarret@iupui.edu
Tammy Garrett, RN
Phone: 317-278-0290


Location Contact:

Indianapolis, Indiana 46202
United States

Jennifer Mohnacky, RDN
Phone: 317-278-2715
Email: jmohnack@iu.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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