Expired Study
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Boston, Massachusetts 02115


Purpose:

The primary purpose of this study is to provide treatment to patients who have participated on a prior protocol investigating Tanespimycin (KOS-953,17-AAG)


Criteria:

Inclusion Criteria: - Age >= 18 years - Participated in and completed a previous Tanespimycin protocol without evidence of unacceptable toxicity and is deemed by the Investigator to be deriving benefit from the Tanespimycin drug as defined in the previous protocol - All patients must rollover to this continuation protocol within 30 days of the last dose of Tanespimycin in the previous protocol, unless previously approved by the Medical Monitor - All Adverse Events from the prior protocol, must have resolved to NCI CTCAE (v. 3.0) Grade <= 2 - The following laboratory results, within 10 days of Tanespimycin administration: - Hemoglobin >= 8 g/dL - Absolute neutrophils count >= 1.0x 10*9* /L - Platelet count >= 50 x 10*9* /L - Serum bilirubin <= 2 x ULN - AST <= 2.5 ULN - Serum creatinine <= 2 x ULN - ECOG performance status of 0, 1 or 2 - Signed informed consent Exclusion Criteria: - Pre-existing neuropathy of CTCAE Grade >= 3 due to any cause - Documented hypersensitivity reaction of CTCAE Grade >= 3 to prior therapy containing Cremophor (for those patients receiving Tanespimycin Injection) - Pregnant or breast-feeding women - Administration of chemotherapy, biological, immunotherapy or investigational agent (therapeutic or diagnostic), excluding Tanespimycin within 21 days prior to receipt of study medication - Any medical conditions that, in the Investigator's opinion, would impose excessive risk to the patient


NCT ID:

NCT00779428


Primary Contact:

Study Director
Bristol-Myers Squibb
Bristol-Myers Squibb


Backup Contact:

N/A


Location Contact:

Boston, Massachusetts 02115
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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