Expired Study
This study is not currently recruiting Study Participants on ClinicalConnection.com. If you would like to find active studies please search for clinical trials.

Durham, North Carolina 27701


Purpose:

The purpose of this study is to look at certain structural changes in the brain in people with bipolar disorder or those with a history of Bipolar disorder. Also collecting a blood sample for genetic testing as relationship of genetics and changes in the brain.


Study summary:

Individuals with bipolar disorder or those with a history of bipolar disorder may have certain structural changes in their brain. The purpose of this study is to look at those changes, as well as the assessment of risk factors for bipolar disorders, involving both social and psychological aspects of behavior, age, education, marital relations, nutrition, physical activity, etc., compared with persons not having bipolar disorder. These changes in the brain will be measured by Magnetic Resonance Imaging (MRI). A blood sample for genetic testing as we will be studying the relationship of genetics and changes in the structure the brain as evidenced by persons having MRI hyperintensities.


Criteria:

Inclusion Criteria: 1. DSM-IV diagnosis of bipolar Disorder, Manic and mixed episodes. 2. 18 years of age and older, male or female, any race. Half the subjects will be above age 50. 3. Capacity to give informed consent and follow study procedures. Exclusion Criteria: 1. History of alcohol/drug dependence 2. Any metal or pacemaker in the body which precludes MRI 3. Pregnancy 4. Dementia or other primary psychiatric disorders including substance abuse/dependence, anxiety disorders, schizophrenia 5. For controls, numbers one through four above as well as any history of depression or the use of antidepressants


NCT ID:

NCT00787930


Primary Contact:

Principal Investigator
John L Beyer, M.D
Duke University

John L Beyer, M.D
Phone: 919.668.0206
Email: beyer001@mc.duke.edu


Backup Contact:

Email: latee002@mc.duke.edu
Nabila Lateef, B.S
Phone: 919-684-9701


Location Contact:

Durham, North Carolina 27701
United States

John L Beyer, M.D
Phone: 919-668-0206
Email: beyer001@mc.duke.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

This study is not currently recruiting Study Participants on ClinicalConnection.com. The form below is not enabled.