La Crosse, Wisconsin 54601


The purpose of this study is to compare Cardiac Magnetic Resonance (CMR) Imaging with transesophageal echocardiography (TEE) in detecting the presence of LAA thrombi in men and women with atrial fibrillation presenting for cardioversion.

Study summary:

The identification of left atrial appendage (LAA) thrombus prior to cardioversion for patients with atrial fibrillation is crucial. LAA thrombus can be a frequent cause of cerebral stroke or peripheral embolism post cardioversion, and anticoagulation therapy is required in these instances to prevent cerebral events and avoid embolization. To date, TEE has been considered the clinical reference in detection of LAA thrombi with high diagnostic accuracy. However, diagnosis and size estimation of LAA thrombi remains challenging due to the complex anatomy of the LAA, and transesophageal echocardiography (TEE) is considered a semi-invasive procedure. To date, there have been few comparative studies involving TEE and cardiac magnetic resonance (CMR) imaging, and the results have been conflicting. With newer CMR Imaging techniques now available, we hypothesize that comparable results will be achieved in detecting LAA thrombus in subjects using a less invasive procedure.


Inclusion Criteria: - atrial fibrillation Exclusion Criteria: - ICDs - pacemakers - intracranial clips - intracranial stimulator devices - insulin pumps - intra ocular metal foreign bodies - cochlear implants - LAA amputation as part of CABG and/or valve surgery - GFR < 60 mL/min



Primary Contact:

Principal Investigator
Raju G Ailiani, MD
Gundersen Lutheran Health System

Raju G Ailiani, MD
Phone: 608-775-2595

Backup Contact:


Location Contact:

La Crosse, Wisconsin 54601
United States

Vicki L McHugh, MS
Phone: 608-775-3857

Site Status: Recruiting

Data Source:

Date Processed: October 09, 2019

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