Bronx, New York 10468

  • Hypercholesterolemia


Recently, research studies have shown that patients who have had trouble taking statins every day, are able to take statins if they take them only once or twice a week. The investigators are doing a research study which involves switching people who are taking ezetimibe to the statin Crestor once or twice a week and to see how ell Crestor lowers cholesterol and if it is tolerated.


Inclusion Criteria: - Patients with a history of intolerance to statins - Patients currently receiving ezetimibe - Patients willing and able to provide signed informed consent Exclusion Criteria: - Patients receiving a statin (Lipitor, Crestor, Lescol, Simvastatin, or Pravachol) - Stroke, TIA, myocardial infarction, unstable angina, percutaneous coronary intervention, coronary artery bypass surgery, or major surgery within 3 months - Cancer undergoing active treatment - Creatinine clearance < 40 ml/minute - Active liver disease or persistent elevation of SGOT or SGPT > 2 times the upper limit of normal level - Participation in any clinical study within the last 30 days - Drug addition or alcohol abuse within the past 6 months - Use of cyclosporine within the last 3 months - Use of gemfibrozil within the last month - Patients unwilling or unable to provide informed consent - Patients with poor compliance - Women of childbearing potential - History of rhabdomyolysis due to statins



Primary Contact:

Principal Investigator
Lawrence Baruch, MD
James J.Peters VA Medical Center

Backup Contact:


Location Contact:

Bronx, New York 10468
United States

Lawrence Baruch, MD
Phone: 718-584-9000

Site Status: Recruiting

Data Source:

Date Processed: December 08, 2022

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