Bethesda, Maryland 20892

  • Unspecified Adult Solid Tumor, Protocol Specific

Purpose:

RATIONALE: Studying samples of blood and/or urine in the laboratory from patients receiving radiation therapy my help doctors learn more about the effects of radiation therapy on cells. It may also help doctors find better ways to treat the cancer. PURPOSE: This research study is looking at the effects of radiation therapy in blood and/or urine samples from patients receiving radiation therapy for cancer.


Study summary:

OBJECTIVES: - Acquire peripheral blood and/or urine samples from patients receiving radiotherapy in the NCI Radiation Oncology Branch. OUTLINE: Samples of blood and/or urine are obtained from patients before, during, and after radiotherapy. Samples are analyzed for expression of genes in white blood cells via cDNA microarray analysis and radiation damage in red blood cells via flow cytometry, VEGF levels in serum and urine via ELISA, profiles of matrix metalloproteinases (MMPs) in urine, and changes in hormones levels in blood and urine. Samples may be stored for future research studies. PROJECTED ACCRUAL: A total of 300 patients will be accrued for this study.


Criteria:

DISEASE CHARACTERISTICS: - Candidate for or currently receiving radiotherapy - Must have obtainable data on any previous radiotherapy PATIENT CHARACTERISTICS: - Not specified PRIOR CONCURRENT THERAPY: - Concurrent immunotherapy, chemotherapy, or hormonal therapy allowed


NCT ID:

NCT00995943


Primary Contact:

Principal Investigator
Kevin Camphausen, MD
NCI - Radiation Oncology Branch; ROB


Backup Contact:

N/A


Location Contact:

Bethesda, Maryland 20892
United States

Patient Recruitment
Phone: 301-496-4891

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: November 27, 2022

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