Kettering, Ohio 45429

  • Mild Traumatic Brain Injury

Purpose:

We will utilize a set of imaging modalities including computed tomography (CT), positron emission tomography (PET), and a suite of magnetic resonance imaging (MRI) tools, to investigate the changes in the human brain resulting from mild traumatic brain injury (mTBI).


Study summary:

We will recruit mTBI subjects and control subjects. Each subject will undergo the set of imaging modalities, and the results will be analyzed for differences at the structural, physiological, and molecular levels. The long term goal of this research is the development of a method to diagnose mTBI based on physical markers. This is a phased project beginning with a pilot study followed by future studies with larger sample sizes.


Criteria:

Inclusion Criteria: Study group: - Between 18 and 55 years of age inclusive. - Potential participant verbally verifies diagnosis of mTBI at pre-screen. - Diagnosed with mild traumatic brain injury by a VAMC physician according to standard diagnostic criteria [12],[13], to be verified by chart review. - Less than 24 months from trauma resulting in mTBI. - Able to read and write in English. - Willingness to refrain from nicotine, and beverages containing either alcohol or caffeine for at least four hours prior to the imaging session. - Have signed the consent form for the study. Control Group: - Between 18 and 55 years of age inclusive. - Potential participant verbally denies history of mTBI at pre-screen. - Able to read and write in English. - Willingness to refrain from nicotine, and beverages containing either alcohol or caffeine for at least four hours prior to the imaging session. - Have signed the consent form for the study Exclusion Criteria: - Conditions that would preclude the completion of a MRI, PET, or CT exam such as claustrophobia, pacemaker, metal objects in body, and/or pregnancy. - Serious, unstable medical or mental illness. - Medical contraindication to any element of the study procedure. - Have not read and signed an informed consent form, or do not understand its contents.


NCT ID:

NCT01044615


Primary Contact:

Principal Investigator
Jason Parker, PhD
Kettering Health Network

Jason Parker, PhD
Phone: 937-395-8483
Email: jason.parker@khnetwork.org


Backup Contact:

N/A


Location Contact:

Kettering, Ohio 45429
United States

Jason Parker, PhD
Phone: 937-395-8483
Email: jason.parker@khnetwork.org

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: November 27, 2022

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

If you would like to be contacted by the clinical trial representative please fill out the form below.