Los Angeles, California 90095

  • Heart Failure

Purpose:

Patients with heart failure cannot exercise as well as those who do not have heart failure, but the exercise dysfunction is not directly attributable to heart dysfunction. Rather, exercise is limited by problems with the skeletal muscles, the muscles in the arms and legs. In this study, the investigators are testing the hypothesis that high adrenaline levels lead to characteristic changes in skeletal muscles, and that interruption of these high adrenaline levels will lead to reversal of these muscle changes and improved exercise ability.


Criteria:

Inclusion Criteria: - heart failure class II-III - LVEF<35% - ages 21-65 - on stable cardiac meds for 3 months Exclusion Criteria: - allergy to clonidine - recent (within 3 months) myocardial infarction - Cr >2 - severe liver dises or pulmonary disease


NCT ID:

NCT01046344


Primary Contact:

Holly R Middlekauff, MD
Phone: 310-206-6672
Email: hmiddlekauff@mednet.ucla.edu


Backup Contact:

N/A


Location Contact:

Los Angeles, California 90095
United States

Holly R Middlekauff, MD
Phone: 310-206-6672
Email: hmiddlekauff@mednet.ucla.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: September 27, 2021

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