Expired Study
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Fort Worth, Texas 76132


To evaluate the effect of BEPREVE compared to a REFRESH Tears Lubricant eye drop on the measurement of the wheal and flare from histamine skin prick testing. This is an open label, two-week, post-marketing study conducted on histamine responsive patients.


Inclusion Criteria: - Healthy male and female subjects, 18 to 65 years of age - Patients must demonstrate a positive reaction to a Histamine skin-prick test. Manifested by a histamine-induced wheal of >3mm in diameter over the normal saline control after 15 minutes of elapsed time Exclusion Criteria: - Significant signs and symptoms of currently active allergic disease (SAR, perennial allergic rhinitis, episodic allergic rhinitis) - Upper respiratory tract infection, sinusitis, asthma or flu-like symptoms within 2 weeks prior to visit 1 - Subjects who have dermatographism or other skin conditions which might interfere with the interpretation of the skin test results - Subjects who are receiving escalating doses of immunotherapy, oral immunotherapy or short course (rush) immunotherapy - Known hypersensitivity to the investigational product or to drugs with similar chemical properties - Pregnancy and/or breast feeding - Use of antihistamines, NSAIDS, steroids, or other drugs which may affect the skin-response - Use of any medications or agents that are not specified above that may confound the interpretation of the results



Primary Contact:

Principal Investigator
Bob Q Lanier, MD
North Texas Institute for Clinical Trials

Backup Contact:


Location Contact:

Fort Worth, Texas 76132
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: August 31, 2019

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