Expired Study
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Cleveland, Ohio 44195


Purpose:

The investigators will evaluate the effects of dexmedetomidine and propofol on cerebral blood flow and brain oxygenation during Deep Brain Stimulation (DBS) surgery. Specifically, the investigators will test the hypothesis that dexmedetomidine is non-inferior to propofol for cerebral blood flow as measured by transcranial Doppler and brain oxygenation as measured by near-infrared spectroscopy.


Criteria:

Inclusion Criteria: - ASA I-III. - Scheduled for DBS. Exclusion Criteria: - History of dystonia. - Severe heart failure with ejection fraction less than 30%. - History of obstructive sleep apnea. - History of renal failure with creatinine level > 2 mg/dl. - Allergies to α-2 agonists and propofol. - Current use of α-2 agonist medications such as clonidine.


NCT ID:

NCT01200433


Primary Contact:

Principal Investigator
Ehab Farag, MD
The Cleveland Clinic


Backup Contact:

N/A


Location Contact:

Cleveland, Ohio 44195
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: August 31, 2019

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