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Gainesville, Florida


The objective of this study is to compare the efficacy of prokinetics versus antibiotics versus a combination of antibiotics plus prokinetics in the eradication of Small-Intestinal Bacterial Over-Growth Syndrome (SIBO) in those with and without a positive D-xylose Breath Test. Hypothesis: Patients with SIBO treated with a combination of prokinetics and in particular octreotide and antibiotics will have reduced recurrence rates of SIBO than either therapy given alone.

Study summary:

We want to determine whether treatment with prokinetics such as Octreotide, Azithromycin, Erythromycin or Tegaserod alone, versus antibiotics alone, or combination of antibiotics plus prokinetics results in symptomatic improvement in patients with SIBO (defined by a positive D xylose Breath test).


Inclusion Criteria: - Patients who have had 14 C-D-Xylose Breath test performed in GI Motility Laboratory at the University of Florida Exclusion Criteria: - Those who cannot tolerate 14 C-D-Xylose Breath test for any reason



Primary Contact:

Principal Investigator
Baharak Moshiree, MD, MS
University of Florida

Backup Contact:


Location Contact:

Gainesville, Florida
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: August 31, 2019

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