San Francisco, California 94110


Purpose:

This study involved the medical record review of resuscitation records for all severely-injured trauma patients requiring emergent surgical intervention and significant acidosis from 2005 through 2009.


Study summary:

The study objective is to assess the efficacy of fluid resuscitation and treatment of acidosis in patients who were managed with use of amine buffer THAM (tris-hydroxymethlaminomethane) versus those who were resuscitated with crystalloids or colloids and may have have received sodium bicarbonate for the treatment of acidosis.


Criteria:

Inclusion Criteria: - Presence of severe traumatic injury requiring emergent surgery - Peri-operative development of severe acidosis (defined arterial ph less than or equal to 7.20 or base deficit greater than or equal to 10 mEq/dL) - Acidosis was treated with either THAM or "usual care" (defined as crystalloid either or without sodium bicarbonate) Exclusion Criteria: - None


NCT ID:

NCT01326260


Primary Contact:

Principal Investigator
Julin Tang, MD
University of California, San Francisco

Julin F Tang, MD
Phone: 415-206-5274
Email: tangj@anesthesia.ucsf.edu


Backup Contact:

Email: pangang@anesthesia.ucsf.edu
Gus Pangan, MBA
Phone: (415) 206-5274


Location Contact:

San Francisco, California 94110
United States

Julin Tang, MD
Phone: 415-206-5274
Email: tangj@anesthesia.ucsf.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: August 31, 2019

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