Boston, Massachusetts 02115


Anaphylaxis is a serious allergic reaction that develops rapidly and can cause death. Some patients experience anaphylaxis is association with exercise, a disorder called exercise-induced anaphylaxis. A subset of patients with unexplained anaphylaxis, especially those with hypotension during the anaphylactic episodes, have been shown to have abnormal, clonal populations of a certain cell type, mast cells, in the bone marrow. This has been described in at least one patient with exercise-induced anaphylaxis. The investigators would like review the findings in a group of patients with exercise-induced anaphylaxis who have undergone evaluation for the presence of abnormal, clonal mast cells.


Inclusion Criteria: - Anaphylaxis in association with exercise on at least two occasions - During anaphylactic reaction, the subject must have experienced one or more of the following: flushing, hypotension, lack of urticaria Exclusion Criteria: - Pregnancy



Primary Contact:


Backup Contact:


Location Contact:

Boston, Massachusetts 02115
United States

Cem Akin, MD, PhD
Phone: 617-732-9227

Site Status: Recruiting

Data Source:

Date Processed: August 31, 2019

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

Click to view Full Listing

If you would like to be contacted by the clinical trial representative please fill out the form below.