Expired Study
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San Antonio, Texas 78209


Purpose:

The primary purpose of this study is to evaluate the pharmacodynamics of LX4211 relative to meals in healthy subjects.


Criteria:

Inclusion Criteria: - Adults ≥18 and ≤55 years of age - Vital signs at Screening in the following ranges: systolic blood pressure, 90-140 mm Hg; diastolic blood pressure, 50-90 mm Hg; heart rate, 50-100 bpm - Body mass index (BMI) ≥18 and ≤35 kg/sq m - Able to provide written informed consent Exclusion Criteria: - Use of any medication (prescription, over-the-counter, herbal tea, or supplements) within 5 days of dosing - Use of any investigational agent or study treatment within 30 days of Day 1 - Use of any protein or antibody-based therapeutic agents within 3 months of Screening - Prior exposure to any SGLT inhibitor - Use of cigarettes or any tobacco products within 6 weeks prior to Screening and while participating in the study - History of bariatric surgery or any other gastrointestinal surgery that may induce malabsorption - History of any major surgery within 6 months of Screening - History of any hypersensitivity to the inactive components of LX4211 - History of renal disease or significantly abnormal kidney function tests - History of hepatic disease or significantly abnormal liver function tests - History of any active infection within 30 days of Day 1 - History of alcohol or substance abuse within 2 years prior to Day 1 - Positive urine glucose at Screening - Positive pregnancy test at Screening - Inability or difficulty swallowing whole tablets or capsules - Unable or unwilling to communicate or cooperate with the Investigator.


NCT ID:

NCT01334242


Primary Contact:

Study Director
Ikenna Ogbaa, MD
Lexicon Pharmaceuticals, Inc.


Backup Contact:

N/A


Location Contact:

San Antonio, Texas 78209
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: August 31, 2019

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