Expired Study
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Baltimore, Maryland 21225


This Phase 1 study will evaluate multiple doses across a range that has been found to be effective in mouse models of asthma and safe in one Phase 1 clinical trial. It is intended to provide evidence of the tolerability of multiple doses as well as provide information on the Pharmacokinetic (PK) and metabolism of N6022 in humans.


Inclusion Criteria: 1. Subject is healthy, determined by pre-study medical evaluation (medical history, physical examination, vital signs, 12-lead ECG, and clinical laboratory evaluations 2. Subject is a non-smoker (or other nicotine user) as determined by history (no nicotine use over the past year) and a negative urine cotinine test at screening and Day 1. 3. Subject has a body weight > 50 kg and BMI between 19.5 and 29.5 kg/m2, inclusive, at screening. 4. Subject has systolic BP > 90 mmHg and diastolic BP > 50 mmHg at screening or Day-1. Exclusion Criteria: 1. Subject has clinically significant history or evidence of cardiovascular, respiratory, hepatic, renal, gastrointestinal, endocrine, neurological, immunological, or psychiatric disorder(s) as determined by the investigator or designee. 2. Subject is a current alcohol abuser and/or has a history of illicit drug abuse within six months of entry. 3. Subject has donated blood (> 500 mL) or blood products within 56 days prior to Day -1. 4. Subject has a history of bleeding disorders (i.e., severe hemorrhage, melena, rectal bleeding, nosebleeds, bruising, etc.).



Primary Contact:

Principal Investigator
Ronald Goldwater, MDCM, MSc(A)
PAREXEL International

Backup Contact:


Location Contact:

Baltimore, Maryland 21225
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: August 31, 2019

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