Irvine, California 92612

  • Abnormal Vascular Flow


The purpose of this research is to evaluate and validate the performance of non-invasive imaging modalities for assessment of skin. A pressure cuff occlusion will be used to stimulate blood flow dynamic that these instruments are designed to sense. The researcher currently plan to assess only basic feasibility of the imaging instruments.

Study summary:

The primary reason for including pressure cuff occlusion in this protocol is to test the performance of Multi-Spectral Imaging and Laser Speckle Imaging can measure in the full range of vascular conditions ranging from ischemic (under-perfused or unsaturated) to hyperemic (over-perfused and over-saturated). 1. .Modulated Imaging a non-contact optical imaging technology can detect the concentration of total hemoglobin, deoxygenated and oxygenated hemoglobin in absolute amounts in units of millimoles / unit volume of tissue measured. 2. . Laser Speckle Imaging a non-contact optical imaging technology consists of a coherent light source, camera, and image acquisition system. This image device can measure and compare relative flow in vasculature at varied time points.


Inclusion Criteria: - Male and female adult 18 years and older Exclusion Criteria: - Younger than 18 years of age - Pregnant women



Primary Contact:

Principal Investigator
Anthony Durkin, PhD
Beckman Laser Institute, UCI

Ata Sharif, MD
Phone: 949-824-9265

Backup Contact:


Location Contact:

Irvine, California 92612
United States

Ata Sharif, MD
Phone: 949-824-9265

Site Status: Recruiting

Data Source:

Date Processed: September 18, 2021

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