New York, New York 10021

  • Infertility

Purpose:

The objectives of this study are to evaluate the clinical efficacy of Natural in vitro Fertilization and in vitro maturation.


Study summary:

Collection of one mature egg from a follicle in the ovary without gonadotropin medications (natural cycle IVF) results in low pregnancy rates. One way to improve natural cycle IVF is to combine this procedure with the removal of immature eggs from the ovary and mature these eggs in the laboratory ( in vitro maturation-IVM). The in vitro mature eggs are fertilized and the resultant embryos are cultured using conventional IVF techniques.


Criteria:

Inclusion Criteria: 1. Each subject must be female. 2. Each subject must have an indication for COH and IVF with or without ICSI. 3. Each subject must be willing and able to provide written informed consent for the trial 4. Each subject must be 25 to ≤42 years of age at the time of signing informed consent. 5. Each subject must have a normal cervical smear result (no atypical or abnormal cells, or in case of atypical squamous or glandular cells, no signs of malignancy; corresponding to Papanicolaou [PAP] I or II) obtained within 12 months prior to signing informed consent must be available Exclusion Criteria: 1. Subject with premature ovarian failure 2. Subject with endocrine abnormalities such as hyperprolactinaemia or thyroid dysfunction 3. Subject with malformation or absence of uterus 4. Subject has tested positive for Human Immunodeficiency Virus (HIV) or Hepatitis B (by local laboratory; results obtained within 1 year prior to signing ICF are considered valid). 5. Subject with contraindication or allergy/hypersensitivity to hCG, estrogen and progesterone


NCT ID:

NCT01550861


Primary Contact:

Principal Investigator
Zev Rosenwaks, MD
Weill Cornell

Rodriq Stubbs, NP
Phone: 646-962-3276
Email: res2011@med.cornell.edu


Backup Contact:

Mitasha Joseph, RN, MPA
Phone: 646-962-3382


Location Contact:

New York, New York 10021
United States

Rodriq Stubbs, NP
Phone: 646-962-3276
Email: res2011@med.cornell.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: December 07, 2022

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.


Click to view Full Listing

If you would like to be contacted by the clinical trial representative please fill out the form below.