New Haven, Connecticut 06519

  • Alcohol Drinking


The primary purpose of the study is to increase our knowledge of receptor function in the brains of people who are heavy drinkers and taking naltrexone (NTX), a medication that has been approved for the treatment of alcohol dependence. Receptors are special molecules in the brain to which other molecules (neurotransmitters) attach during the normal every-day workings of the brain. Drugs can bind to those receptor molecules as well. Recent evidence suggests that kappa opioid receptors (KOR's) may play an important role in alcohol drinking behavior. This study will try to determine if naltrexone's ability to attach to these receptors is related to its effectiveness. We will use PET (positron emission tomography) for this study. PET is a type of imaging device found in nuclear medicine. It is used for tracking the presence of injected radioactive materials in the body.


Inclusion Criteria: - Ages 21-50 - Able to read English at 6th grade level or higher and to complete study evaluations - Regular alcohol drinker Exclusion Criteria: - Individuals who are seeking alcohol treatment - Medical conditions that would contraindicate the use of study medication - Regular use of other substances



Primary Contact:

Principal Investigator
Suchitra Krishnan-Sarin, Ph.D.
Yale University

Backup Contact:


Location Contact:

New Haven, Connecticut 06519
United States

Nicholas Franco, B.A.
Phone: 203-974-7679

Site Status: Recruiting

Data Source:

Date Processed: September 18, 2021

Modifications to this listing: Only selected fields are shown, please use the link below to view all information about this clinical trial.

Click to view Full Listing

If you would like to be contacted by the clinical trial representative please fill out the form below.