New York, New York 10021

  • Post Operative Pain

Purpose:

The purpose of this research study is to investigate whether or not platelet rich plasma (PRP) may help to improve tendon healing and decrease post operative pain in patients undergoing anterior cruciate ligament (ACL) reconstructive surgery using their own patellar tendons as autografts.


Study summary:

There is currently a paucity of well-designed, prospective, randomized, blinded (Level 1) clinical studies that carefully and comprehensively investigate the role of PRP in ACL surgery. Specifically, ACL reconstruction using Bone Patellar Tendon Bone (BPTB) harvest and the role of PRP in decreasing postoperative pain at the donor site. Given the need for a highly powered study to demonstrate the clinical efficacy of PRP in ACL reconstruction, the investigators have designed a prospective, randomized, level 1, double-blinded study to evaluate the effects of PRP on the specific outcomes of donor site pain and radiographic measures of graft healing and incorporation. The aim of this study is to evaluate the efficacy of intra-operatively applied autologous PRP in reducing donor site morbidity and increasing radiographic healing in ACL reconstruction using autologous BPTB.


Criteria:

Inclusion Criteria: - Primary ACL Reconstruction - Outerbridge </= 2 - Minimum follow up of two years - No ligamentous secondary injury - Willingness to participate in study Exclusion Criteria: - Any previous knee injury - prior history of anterior knee pain - Outerbridge classification 3 or greater - Revision ACL - Diabetic or smoker - Workers compensation patient - pregnant or nursing women - Any patient with limited English Proficiency


NCT ID:

NCT01765712


Primary Contact:

Principal Investigator
Stephen Nicholas, MD
Northwell Health


Backup Contact:

N/A


Location Contact:

New York, New York 10021
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: June 16, 2021

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