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Bryn Mawr, Pennsylvania 19010


Asthma in the elderly is poorly understood, as most studies have not included this patient group. In a previous study of adults with asthma, choline supplementation had a positive effect on asthma symptoms and allowed to decrease asthma pharmacologic treatment. The present study is a randomized, double-blind, placebo-controlled, cross-over study of choline supplementation. The investigators will study the effect of choline 650 mg taken orally twice daily x 6 weeks versus placebo on asthma symptom scores (Asthma Control Test) and spirometric values (FEV1, FEV1/FVC, FEF25-75%). The investigators will also look at the effect of choline supplementation on peripheral blood eosinophils, serum immunoglobulin E (IgE) and homocysteine levels.


Inclusion Criteria: - Asthma Exclusion Criteria: - No history of smoking more than 10 pack/years, - no gastrointestinal cancers, - no liver or kidney disease, - no bipolar disorder.



Primary Contact:

Principal Investigator
Michele Columbo, M.D.
Rohr and Columbo Asthma, Allergy and Immunology Specialists

Backup Contact:


Location Contact:

Bryn Mawr, Pennsylvania 19010
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: June 25, 2018

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