Expired Study
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Pheonix, Arizona 85014


Purpose:

The objectives of this study are to evaluate the safety and tolerability of Zimura® intravitreous injection in combination with anti-VEGF therapy in subjects with Idiopathic Polypoidal Choroidal Vasculopathy (IPCV).


Study summary:

Treatment experienced (Prior treatment with anti-VEGF monotherapy of ≥8 injections in the previous twelve (12) months) subjects with IPCV will receive 3 monthly (Q4W) injections of Zimura® in combination with anti-VEGF therapy.


Criteria:

Inclusion Criteria: - Subjects of either gender aged ≥ 50 years - Diagnosis of IPCV - Treatment-experienced defined as prior treatment with anti-VEGF mono therapy of ≥ 8 injections in the previous twelve (12) months Exclusion Criteria: - Any intraocular surgery or thermal laser within three (3) months of trial entry - Any prior thermal laser in the macular region, regardless of indication - Any ocular or periocular infection in the twelve (12) weeks prior to entry - History of any of the following conditions or procedures in the study eye: Rhegmatogenous retinal detachment, pars plana vitrectomy, filtering surgery (e.g. trabeculectomy), glaucoma drainage device, corneal transplant - Previous therapeutic radiation in the region of the study eye - A diagnosis of diabetic retinopathy (presence of microaneurysms or any vasculopathy and/or leakage from retinal vasculature in a subject with diabetes mellitus)


NCT ID:

NCT02397954


Primary Contact:

N/A


Backup Contact:

N/A


Location Contact:

Pheonix, Arizona 85014
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: June 25, 2018

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