Indianapolis, Indiana 46202


The goal of this protocol is to obtain information from individuals with cardiomyopathy and from their families in order to elucidate the molecular genetics of this disorder. This will provide the basis for future genetic counseling as well as contribute to elucidating the biology of normal and abnormal cardiac function.

Study summary:

Cardiomyopathy is a genetically heterogeneous heart muscle disorder that results in ventricular dysfunction. While significant progress has been made in identifying the genetic basis of cardiomyopathy in adults, molecular diagnosis in children has proven more challenging and current algorithms do not incorporate mutation analysis in the clinical protocol. However, recent studies indicate that cardiomyopathy outcomes in children are origin specific, highlighting the importance of precise diagnosis. The goal of this study is to identify the genetic causes of pediatric cardiomyopathy. Rapid, comprehensive and cost-effective detection of genetic causes of cardiomyopathy will aid management and development of novel treatment strategies.


Inclusion Criteria: - Subjects with cardiomyopathy - Family members of subjects with cardiomyopathy Exclusion Criteria: - Subjects without cardiomyopathy - Family members of subjects without cardiomyopathy



Primary Contact:

Principal Investigator
Stephanie Ware, MD, PhD
IU School of Medicine

Lindsey Elmore, BS, BA
Phone: (317) 278-3020

Backup Contact:

Stephanie Ware, MD, PhD
Phone: (317) 278-2807

Location Contact:

Indianapolis, Indiana 46202
United States

Stephanie Ware, MD, PhD
Phone: 317-278-2807

Site Status: Recruiting

Data Source:

Date Processed: January 21, 2020

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