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Boston, Massachusetts 02129


Depression one of the leading causes of disability worldwide. Individuals suffering from depression typically exhibit impairments in various mental abilities, such as the ability to effectively direct and control attention and the ability to switch between thinking about different things and concepts (commonly referred to as "cognitive flexibility"). Mindfulness meditation training is a technique which involves focusing one's awareness on the present moment, while calmly acknowledging and accepting one's feelings, thoughts, and bodily sensations. It has been well documented to improve depressive symptoms and prevent recurrence of depressive episodes, yet little is known about how mindfulness does so and what are the underlying mental mechanisms involved. Here the investigators propose to examine the efficacy of an 8-week mindfulness training program in improving the ability to direct and control attention, as well as in cognitive flexibility. Individuals diagnosed with recurrent depression will undergo an 8-week mindfulness training program. Participants' depressive symptoms as well as their performance on measures of attention and cognitive flexibility will be examined. Participants will be assigned to mindfulness training or a wait-list control group. Half of the participants will be examined before and after the mindfulness training program and the other half will be tested 8-weeks apart and then begin their training.


Inclusion Criteria: - Reporting dysphoria for at least two months prior - HAM-D score of at least 11 - No history of psychiatric disorders of psychotic features, neurological disorders, or substance abuse in the past 6 months - Verified age between 18-65 years old - Had no suicidal attempts during the past six months - No prior experience with MBCT or other systematic meditation programs Exclusion Criteria: - History of psychosis, neurological disorder, and substance abuse for the past 6 months - Suicide attempt in past 6 months - Prior experience with MBCT or other systematic meditation program



Primary Contact:

Principal Investigator
Jonathan Greenberg, PhD
Massachusetts General Hospital

Backup Contact:


Location Contact:

Boston, Massachusetts 02129
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: November 18, 2019

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