Expired Study
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Rochester, Minnesota 55905


The purpose of this study was to determine the effects (good and bad) of giving a drug called pentoxifylline to patients with acute pancreatitis.

Study summary:

Participants were randomized to either the treatment group (Pentoxifylline medication) or the control group (Placebo). Participant took a pill orally, starting from the time of admission. Participants received a total of 9 doses over the three days of hospitalization (72 hours). Research blood draws were done at baseline and on 5 successive days or until the time of discharge, whichever occured earlier. The study gathered clinical follow up information up to 4 months following hospitalization regarding the diagnosis of acute pancreatitis.


Inclusion criteria - Enrollment within 72 hours of diagnosis of acute pancreatitis (AP) - Ability to give informed consent or a Legal Adult Representative (LAR) able to give informed consent for subject when needed as defined buy LAR use guidelines. - Adult subjects of age ≥18 years. Exclusion Criteria: - Moderate or severe congestive heart failure - History of seizure disorders or demyelinating disease - Nursing mothers - Pregnancy - History of prior tuberculosis or risk factors for tuberculosis - Evidence of non- corticosteroid immunosuppression (such as malignancy, chronic renal failure, chemotherapy within 60 days, and HIV) - Evidence of active hemorrhage - Paralytic ileus with severe nausea and vomiting



Primary Contact:

Principal Investigator
Santhi Swaroop Vege, MD
Mayo Clinic

Backup Contact:


Location Contact:

Rochester, Minnesota 55905
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: November 18, 2019

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