Expired Study
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Glendale, California 91206


Purpose:

This study involves single and multiple doses of LY3202626 and will evaluate the effects of LY3202626 on the body. There will be 4 parts to this study. In Parts A and B, single increasing doses of LY3202626 will be given in capsule form. Part A will also include itraconazole given orally as a solution. Part A will last approximately 8-12 weeks. Part B will last approximately 5-6 weeks. In Parts C and D, participants will be dosed multiple days with the study drug. Part C will last approximately 11-14 weeks. Part D will last approximately 11-14 weeks and participants must have Alzheimer's Disease. Participants may only enroll in one part.


Criteria:

Inclusion Criteria: - For Parts A, B, and C, are overtly healthy males or females (nonchildbearing potential), as determined by medical history and physical examination - Have a body mass index (BMI) of 18 to 32 kilograms per square meter (kg/m^2) - For Part D, present with Mild Cognitive Impairment (MCI) due to Alzheimer's Disease (AD) or mild to moderate AD - Have venous access sufficient to allow for blood sampling - Are reliable and willing to make themselves available for the duration of the study and are willing to follow study procedures and research unit policies Exclusion Criteria: - Taking over-the-counter or prescription medication with the exception of vitamins or minerals - Smoke more than 10 cigarettes per day - Are unwilling or unable to refrain from eating any food or drinking any beverage containing grapefruit or grapefruit juice for at least 2 weeks prior to first dose until completion of the study


NCT ID:

NCT02323334


Primary Contact:

Study Director
Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 9 AM - 5 PM Eastern time (UTC/GMT - 5 hours, EST)
Eli Lilly and Company


Backup Contact:

N/A


Location Contact:

Glendale, California 91206
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: January 21, 2020

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