Jacksonville, Florida 32224


Purpose:

The primary aim of this study is to establish the practicality of using two novel imaging modalities for the assessment of biomechanical properties of the aorta.


Study summary:

Patients with Abdominal Aortic Aneurysm, (AAA), will be identified within the vascular surgery practice. Those patients who meet standard indications for surgery including symptomatic AAA, size >5.0-5.5 cm, or rapidly enlarging >0.5 cm per 6 months will have standard pre-operative work-up which includes magnetic resonance angiogram (MRA) and Echocardiogram (ECHO). These pre-operative studies will be modified for the study patients to include electrocardiogram(ECG)-gating (coupled with MR angiogram) and 2-Dimensional speckle-tracking ultrasound of the abdominal aorta. Patients in the study will be followed for 1 year. Measurements will be analyzed for any relationship between aortic wall properties and clinical outcomes such as aneurysm growth, rupture risk or aortic dissection. This study will be comparing 3 groups of patients: no surgery (surveillance), open surgery, and endovascular aneurysm repair (EVAR).


Criteria:

Inclusion Criteria: - Patients >18 years of age with ability to provide informed consent. - Patients with either symptomatic or asymptomatic AAA as defined by aortic diameter ≥ 1.5x normal diameter. - Patients with non-aneurysmal aortas who require aortic contrast imaging or echocardiography for preoperative planning or other reason. Exclusion Criteria: - Patients with contraindication to IV contrast such as allergy or severe kidney dysfunction. - Patients who do not require contrast imaging or echocardiogram as part of their care plan. - Terminally ill patients, and patients with estimated life expectancy of ≤ 6 months. - Patients unable to tolerate magnetic resonance imaging.


NCT ID:

NCT02548546


Primary Contact:

Houssam Farres, MD
Phone: 904-953-2077
Email: farres.houssam@mayo.edu


Backup Contact:

Email: buchanan.mauricia@mayo.edu
Mauricia Buchanan, RN
Phone: 904-953-2077


Location Contact:

Jacksonville, Florida 32224
United States



There is no listed contact information for this specific location.

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: January 21, 2020

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