Expired Study
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Hershey, Pennsylvania 17033


The purpose of this study is to examine healing after rotator cuff repair in subjects either treated with Doxycycline or placebo post-operatively.

Study summary:

Basic Science small animal model data indicates that matrix metalloproteinase (MMP) inhibition via doxycycline results in improved early rotator cuff repair biomechanics and histology. Rotator cuff repair failure and retear is a significant clinical problem. The effects of MMP inhibition on human rotator cuff tear repair healing and outcomes is unknown, but may potentially improve healing rates and outcomes. Our purpose is to evaluate the effects of early oral doxycycline on healing and outcomes following arthroscopic rotator cuff repair.


Inclusion Criteria: - repair of rotator cuff - age 18 and above - able to swallow capsules Exclusion Criteria: - less than 18 - unable to read or understand consent form - unable to swallow capsules - allergy to doxycycline



Primary Contact:

Principal Investigator
Aman Dhawan, MD
Milton S. Hershey Medical Center

Backup Contact:


Location Contact:

Hershey, Pennsylvania 17033
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: November 18, 2019

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