Expired Study
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San Antonio, Texas 78209


The purpose of this study is to evaluate the relative bioavailability of a single 300 mg dose of GBT440 administered as a high strength (1 × 300 mg) capsule versus a low strength (3 × 100 mg) capsule formulation in healthy fasted subjects.


Inclusion Criteria: - Subject is a female of non-childbearing potential or male, who is healthy, nonsmoking, and 18 to 60 years old, inclusive, at screening - Male subjects agree to use contraception - Willing and able to give written informed consent Exclusion Criteria: - Evidence or history of clinically significant metabolic, allergic, dermatological, hepatic, renal,hematological, pulmonary, cardiovascular, gastrointestinal, neurological, or psychiatric disorder - History of hypersensitivity or allergy to drugs, foods, or other substances - History or presence of abnormal electrocardiogram or hypertension - History of alcohol abuse, illicit drug use, significant mental illness, physical dependence to any opioid, or any history of drug abuse or addiction within 1 year of screening - Participated in another clinical trial of an investigational drug within 30 days (or 5 half-lives of the investigational drug, whichever is longer) prior to Screening



Primary Contact:

Study Director
Carla Washington, PhD
Global Blood Therapeutics

Backup Contact:


Location Contact:

San Antonio, Texas 78209
United States

There is no listed contact information for this specific location.

Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: January 21, 2020

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