Durham, North Carolina 27705


Purpose:

There are two major goals of this investigation. First, to develop pilot data to justify a larger randomized clinical trial of an intervention designed to train interoceptive signals (IS) and interoceptive responsivity (IR) in persons with Anorexia Nervosa (AN). Second, the investigators will determine whether persons with AN have similar or different IS and IR for heart rate while exercising as compared to age and gender matched controls.


Study summary:

The purpose of this pilot investigation is to assess AN interoceptive sensitivity and responsivity as it pertains to heart rate during exercise. Thirty adults, 18 years and older will be recruited for a cross-sectional comparison of IS and IR in the context of exercise.


Criteria:

Inclusion Criteria: Study participants will include adults with anorexia spectrum disorders and healthy age and gender matched controls. There will be two control groups, one that includes regularly exercising age and gender matched persons and one where controls do not engage in regular exercise. For those with AN, the following INCLUSION criteria must be met: - Age ≥ 18 years old - BMI 25 kg/m2 or less - Diagnosis of anorexia spectrum disorder - Medications: Stable use of all medications ≥ three months For age and gender matched controls, the following INCLUSION criteria must be met: - Age ≥ 18 years old - BMI 25 kg/m2 or less - No diagnosis of anorexia spectrum disorder - Medications: Stable use of all medications ≥ three months - Age (+/- 2 years) and gender matched to study participant Exclusion Criteria: - History of diabetes, heart disease or taking medications for those conditions - History of hypertension (high blood pressure) not controlled with medication - Orthopedic limitations, musculoskeletal disease and/or injury - Inability to consent - Lack of transportation to the Duke Center for Living campus


NCT ID:

NCT02579018


Primary Contact:

Principal Investigator
Nancy L Zucker, PhD
Director, Duke Center for Eating Disorders

Lucy W Piner, MS
Phone: 919-660-6781
Email: lucy.piner@dm.duke.edu


Backup Contact:

Email: kim.huffman@dm.duke.edu
Kim M Huffman, MD
Phone: 919-668-1644


Location Contact:

Durham, North Carolina 27705
United States

Lucy W Piner, MS
Phone: 919-660-6781
Email: lucy.piner@duke.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: January 21, 2020

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