Expired Study
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Boston, Massachusetts


Purpose:

The purpose of this study is to determine whether individualized ventilatory management combining the use of low tidal volumes, alveolar recruitment maneuvers, individually titrated positive end-expiratory pressure and postoperative individualized ventilatory support will decrease postoperative complications, unplanned ICU readmissions, ICU and hospital length of stay and mortality compared to a standardized Lung Protective Ventilation (LPV) for all patients at risk.


Criteria:

Inclusion Criteria: - Age not less than 18 - Risk of postoperative pulmonary complication moderate-high defined by a score ≥ 26 on the risk scale ARISCAT (based on the analysis of seven factors, where a score between 26 and 44 points defines a moderate risk, and a score> 44 points define a high risk, included in the Information Booklet Investigator). - Planned abdominal surgery> 2 hours. - Signed informed consent for participation in the study. Exclusion Criteria: - Age less than 18 years. - Pregnant or breast-feeding. - Patients with BMI >35. - Syndrome of moderate or severe respiratory distress: PaO2/FiO2 < 200 mmHg. - Heart failure: NYHA IV. - Hemodynamic failure: CI <2.5 L/min/m2 and / or requirements before surgery ionotropic support. - Diagnosis or suspicion of intracranial hypertension (intracranial pressure> 15 mmHg). - Mechanical ventilation in the last 15 days. - Presence of pneumothorax. Presence of giant bullae on chest radiography or computed tomography (CT). - Patient with preoperatively CPAP. - Participation in another experimental protocol at the time of intervention selection.


NCT ID:

NCT02158923


Primary Contact:

Study Director
Carlos Ferrando, MD, PhD
Hospital Clínico Universitario Valencia


Backup Contact:

N/A


Location Contact:

Boston, Massachusetts
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: November 18, 2019

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