Expired Study
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La Jolla, California 92037


Purpose:

Recent data suggests that melatonin, a supplement available over the counter, may help prevent delirium in hospitalized patients. The investigators are hypothesizing that melatonin may help in delirium prevention by improving sleep quality and possibly circadian rhythm cycling in patients who are given the supplement. This pilot study involves a randomized placebo-controlled design in which participants will be randomized to receive either melatonin 3mg orally or placebo orally. Participants in both groups will be fitted with wireless actigraphy devices to obtain objective sleep quality, and will also receive a sleep questionnaire each morning to obtain subjective data on their sleep quality overnight. Delirium will be assessed by floor nurses twice daily using the Confusion Assessment Method (CAM).


Criteria:

Inclusion Criteria: - 65-100 years old - Admitted to Scripps Green Hospital - Admitted to an Internal Medicine or Medicine Consult Service - Expected to have a hospital stay of greater than or equal to 48 hours (patients admitted to "inpatient," not "observation," under Medicare guidelines) Exclusion Criteria: - Cirrhosis of any etiology - Admitted for alcohol withdrawal - Currently taking a 1st or 2nd generation anti-psychotic - Active delirium (i.e., delirium prior to 1st dose of melatonin) - Diagnosis of encephalitis - History of seizure


NCT ID:

NCT02597231


Primary Contact:

Principal Investigator
Thomas McCarthy, MD
Scripps Health


Backup Contact:

N/A


Location Contact:

La Jolla, California 92037
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: November 18, 2019

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