Stanford, California 94305


Purpose:

The purpose of this trial is to determine if using abdominal nerve blocks when patient undergo breast reconstruction can significantly decrease use of pain medications after reconstructive surgery.


Study summary:

Primary Objective: The primary objective is to determine if pre-operative transversus abdominis plane (TAP) blocks with continued infusion of local anesthetic post-operatively affect post-operative narcotic usage as compared to a placebo TAP block. Secondary Objective: - To determine if pre-operative TAP blocks with continued infusion of local anesthetic post-operatively affect post-operative pain scores as compared to a placebo TAP block. - To determine if pre-operative TAP blocks with continued infusion of local anesthetic post-operatively affect anti-emetic usage as compared to a placebo TAP block. - To determine if pre-operative TAP blocks with continued infusion of local anesthetic post-operatively affect time to ambulation post-operatively as compared to a placebo TAP block. - To determine if pre-operative TAP blocks with continued infusion of local anesthetic post-operatively affect time to first bowel movement as compared to a placebo TAP block. - To determine if pre-operative TAP blocks with continued infusion of local anesthetic post-operatively affect patient-reported quality of life as compared to a placebo TAP block.


Criteria:

Inclusion Criteria - Prior diagnosis or presumed diagnosis of breast cancer or undergoing prophylactic treatment. - Greater than 18 years old. - Female. - Undergoing microsurgical breast reconstruction with abdominal free flap. - Ability to understand and the willingness to sign a written informed consent document. Exclusion Criteria - True allergy to local anesthetics or opioids. - History of addiction to narcotics within the last 24 months - History of chronic pain on opioids within the last 24 months. - Specific mental health issues such as schizophrenia or bipolar disorder. - Patients who are pregnant.


NCT ID:

NCT02601027


Primary Contact:

Principal Investigator
Gordon K. Lee, MD
Stanford University


Backup Contact:

N/A


Location Contact:

Stanford, California 94305
United States

Afaaf Shakir
Email: ashakir@stanford.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: November 18, 2019

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