La Jolla, California 92093


Purpose:

This is a randomized study to compare Compensatory Cognitive Training (CCT) versus Recreational Therapy (RT) in Latino clinical high risk individuals in the US and Mexico. Study hypotheses: Compared to those who receive RT, study participants receiving CCT will show significant improvement in neurocognition, functional capacity, self-rated functioning and clinical measures.


Study summary:

This is a 12 week randomized study to compare Compensatory Cognitive Training (CCT) versus Recreational Therapy (RT) in Latino clinical high risk individuals in the US and Mexico. Study participants will be measured 3 times, at baseline, 12 and 24 weeks on all outcome measures. Study hypothesis: Study participants receiving CCT will show significant improvement at 12 and 24 weeks compared to baseline in 1) Neurocognition using the Global Cognitive Index z score derived from the MATRICS neurocognitive domain scores, 2) Functional Capacity as assessed by the UCSD Performance-based Skills Assessment (UPSA/UPSA-Adolescent), 3) Self-Rated Functioning as measured by the Specific Level of Functioning Scale (SLoF) and 4) Clinical symptom ratings as measured by the Scale of Prodromal Symptoms (SOPS) total score when compared to subjects receiving RT training across study time.


Criteria:

Inclusion Criteria: - Meet Clinical High Risk criteria - Be of Latino descent - Speak Spanish as their preferred language Exclusion Criteria: - Concomitant medical or neurological illness - Brain injury with loss of consciousness > 30 minutes - Current substance abuse (excluding nicotine) - IQ < 80 - High suicidal risk


NCT ID:

NCT02245607


Primary Contact:

Principal Investigator
Kristin Cadenhead, MD
University of California, San Diego

Kristin Cadenhead, MD
Phone: 619-543-6445
Email: kcadenhead@ucsd.edu


Backup Contact:

N/A


Location Contact:

La Jolla, California 92093
United States



There is no listed contact information for this specific location.

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: January 21, 2020

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