Denver, Colorado 80221

  • Anesthesia, Local

Purpose:

A randomized controlled trial to determine if pre- and post- operative regional pain control (transversus abdominis plane block) with ropivacaine versus placebo leads to lower anesthetic and narcotic dosing, and alters pain scores. This study plans to learn more about regional anesthesia and pain control during abdominal surgery. The study will gather data about the effectiveness of continuous catheter infusion of local anesthetic after an abdominal operation. Outcomes include pain scores, IV pain medicine requirements, and delirium.


Criteria:

Inclusion Criteria: - Age >=50 years. - Subjects will be undergoing an elective intra-abdominal or abdominal wall operation, including pelvic operations. Surgery specialties included are general surgery, surgical oncology, urology, gynecology, plastic surgery. Exclusion Criteria: - Subjects with a history of dementia or aphasia, as visual analog scale and confusion assessment will be unreliable. - Patients with an epidural or spinal catheter block. - Patients who do not speak English so that a language barrier is not confused with VAS scoring or confusion. - Patients who are abusing alcohol defined by a high AUDIT score (>8) will be excluded. - History of bipolar disorder or a psychotic disorder (such as a psychotic major depression, schizophrenia, schizoaffective disorder, or psychosis in Alzheimer's disease or other dementia). - Patients with a documented allergy to ropivacaine or other sodium channel blockers.


NCT ID:

NCT03149783


Primary Contact:

Principal Investigator
Thomas Robinson, MD
University of Colorado, Denver

Douglas Overbey, MD
Phone: 573-225-7728
Email: douglas.overbey@ucdenver.edu


Backup Contact:

Email: thomas.robinson@ucdenver.edu
Thomas Robinson, MD
Phone: 303-399-8020 Ext. 2952


Location Contact:

Denver, Colorado 80221
United States

Thomas Robinson, MD
Phone: 303-399-8020
Email: thomas.robinson@ucdenver.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: September 17, 2021

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