Houston, Texas 77030


Purpose:

This trial studies how well magnetic resonance whole body diffusion-weighted imaging works in finding cancer that has spread to the bone or lymph nodes (metastasis) in participants with high-risk prostate cancer. Diagnostic procedures, such as magnetic resonance whole body diffusion-weighted imaging (a method to show how water moves in a certain area) may help find bone or lymph nodes metastasis.


Study summary:

PRIMARY OBJECTIVES: I. To compare accuracies of whole body magnetic resonance imaging (MRI) versus bone scan plus computed tomography (CT) scan in detecting bone or lymph node metastasis in high risk prostate cancer patients. OUTLINE: Participants undergo standard of care bone scan, CT of the abdomen and pelvis, and pelvic MRI. Participants also undergo magnetic resonance whole body (WB)-diffusion-weighted imaging (DWI) over 20-30 minutes.


Criteria:

Inclusion Criteria: - Prostate carcinoma patients at high risk for metastasis with prostate-specific antigen (PSA) more than 20 ng/ml and/or Gleason score = 8/ > 8. - Ability to understand and sign informed consent. Exclusion Criteria: - Patient is at low risk for metastasis with Gleason score at diagnosis < 8. - Currently receiving or history of systemic therapy with testosterone suppressing medication (i.e., lupron, degarelix, abiraterone, enzalutamide) or local radiation therapy. - Contraindication to magnetic resonance imaging (MRI).


NCT ID:

NCT03085043


Primary Contact:

Principal Investigator
Tharakeswara K Bathala
M.D. Anderson Cancer Center

Tharakeswara K. Bathala, MBBS,MD
Phone: 713-792-2533
Email: TKBathala@mdanderson.org


Backup Contact:

N/A


Location Contact:

Houston, Texas 77030
United States

Tharakeswara K. Bathala
Phone: 713-792-2533

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: January 21, 2020

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