Expired Study
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Dallas, Texas 75390


Purpose:

Determine whether CT-based multiparametric analytical models may improve prediction of biopsy and treatment outcome in patients undergoing screening CT scan and/or treatment for early stage lung cancer


Study summary:

The hypothesis is that multiparametric models that incorporate complex image information from screening CT scans will improve prediction of the outcome of subsequent lung biopsy, an invasive diagnostic procedure. In this project, we will construct an image feature-based multiparametric prognostic model for biopsy outcome from screening lung CT scans performed at our institution, and then validate it using theNLST imaging and clinical outcomes dataset. This study involves no treatment or invasive procedures. Investigator will review all charts of patients who were treated for early stage lung cancer with definitive radiation therapy at UTSW or Parkland Memorial hospital, diagnosed with a malignancy from January 1, 2004 to October 31, 2014, to compile demographic, diagnostic, therapeutic, outcome, and toxicity data. Investigator expect that this will include approximately 200 patient charts. This data will be analyzed statistically and used for future directed research. Investigator will also analyze an anonymized dataset of patients from the National Lung Cancer Screening Trial (NLST) provided by the National Cancer Institute (NCI)


Criteria:

Inclusion Criteria: 1) Patients that have been diagnosed with lung cancer, and are treated at Department of Radiation Oncology, UTSW. 2Patients are greater than 18 years of age. 3)Patients understand a written informed consent document and are willing to sign the consent form. 4)The tumor must be ineligible for definitive surgical resection. Exclusion Criteria: 1. Women who are pregnant or trying to get pregnant 2. Children (under age of 18) 3. The tumor must be ineligible for stereotactic body radiation therapy. 4. Chemotherapy given within one week of study registration. 5. Evidence of small cell histology.


NCT ID:

NCT03563976


Primary Contact:

N/A


Backup Contact:

N/A


Location Contact:

Dallas, Texas 75390
United States



There is no listed contact information for this specific location.

Site Status: N/A


Data Source: ClinicalTrials.gov

Date Processed: February 04, 2019

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