New York, New York 10016


The objective of this trial is to measure the changes in neural activities during tDCS session using Magnetic Resonance Imaging (MRI). Participants (N=60) (20 Healthy Controls and 40 participants with neurological disorders, ie. multiple sclerosis) will be recruited to complete self-report measures and a brief cognitive assessment and then undergo an hour long stand-alone MRI scan while simultaneously undergoing tDCS stimulation. Methodology for this study is the administration of 15-minutes of of active tDCS during MRI acquisition compared to time without active tDCS.


Inclusion Criteria: - Standardized SDMT Z-scores ≥3 standard deviations below mean - Able to understand all study instructions and supply written consent Exclusion Criteria: - Extreme claustrophobia - History of mental retardation, pervasive developmental disorder or other neurological condition associated with cognitive impairment - Primary psychiatric disorder that would influence ability to participate - History of seizures or seizure disorder - History of head trauma in the past year (e.g., head injury, brain surgery) or medical device implanted in the head (such as Deep Brain Stimulator) or in the neck (such as a Vagus Nerve Stimulator) - Any skin disorder/sensitive skin (e.g., eczema, severe rashes), blisters, open wounds, burn including sunburns, cuts or irritation, or other skin defects which compromise the integrity of the skin at or near stimulation locations (where electrodes are placed) - Treatment for a communicable skin disorder currently or over the past 12 months - History of uncontrolled or labile hypertension. - Have any irremovable piercings, implantations or metallic-based tattoos - History of clinically significant abnormalities on electrocardiogram (EKG) - Pregnant or breastfeeding - Current substance abuse disorder



Primary Contact:

Principal Investigator
Leigh Charvet, MD
New York University School of Medicine

Kai Sherman
Phone: 929 455 5125

Backup Contact:


Location Contact:

New York, New York 10016
United States

Kai Sherman, MD
Phone: 929-455-5125

Site Status: Recruiting

Data Source:

Date Processed: February 04, 2019

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