Nashville, Tennessee 37212


The researchers propose to study how functional nausea in adolescents may be characterized noninvasively by the use of multichannel electrogastrogram (EGG) and magnetogastrogram (MGG) recordings.

Study summary:

Functional nausea (FN) is a GI disorder that affects millions of Americans, particularly adolescents, but diagnoses remain largely exclusionary relying on symptomology with an otherwise normal diagnostic workup. Successful completion of the project could contribute to understanding the altered physiology of functional nausea (FN), to stratification of FN patients according to physiological and/or psychological phenotypes, to improve diagnosis and provide objective measures of nausea and to inform and guide treatment options. The analysis of slow wave activity represents the first physiologically-quantifiable noninvasive assessment method for pathological processes associated with functional nausea in adolescents.


Inclusion Criteria: - children ages 8-17 with functional nausea - normal control participants ages 8-17 who have no known gastrointestinal complications Exclusion Criteria: - Those with claustrophobia who cannot lie still under the SQUID for the length of time required. - Normal participants with known intestinal complications - Patients with cyclic vomiting syndrome, gastroparesis, malignancy, primary eating disorders, pregnancy, or hyperglycemia - Morbid obesity (these patients are presumably unable to lie under the current generation of SQUID devices). - Patients with a history of cardiac arrhythmias or taking anticoagulants will be excluded



Primary Contact:

Principal Investigator
Alan Bradshaw, Ph.D.
Vanderbilt University

Melissa Beavers
Phone: 615-936-7017

Backup Contact:


Location Contact:

Nashville, Tennessee 37212
United States

Melissa Beavers
Phone: 615-936-7017

Site Status: Recruiting

Data Source:

Date Processed: February 04, 2019

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