Urbana, Illinois 61801

  • Inflammation


Recent evidence has shown that obese and overweight children exhibit states of chronic inflammation. In obese adults, a high carbohydrate meal induces an inflammatory response; however, the effects of a high carbohydrate meal on biomarkers of inflammation has not previously been examined in children. The purpose of this research project is to characterize the inflammatory response to a high carbohydrate versus a low carbohydrate meal in healthy weight, overweight, and obese children (age 7-17 years). After completing informed consent/assent, a Dual-energy X-ray Absorptiometry (DXA) scan, and baseline blood draw on experimental day 1, children will then return to the lab two times to ingest either a high or low carbohydrate beverage followed by post-meal blood collection for a total of 3 blood draws. Biomarkers of inflammation will be analyzed by flow cytometry and enzyme-linked immunosorbent assay (ELISA). Participants will be recruited through various studies through the Neurocognitive Kinesiology Lab/Body Composition and Nutritional Neuroscience Labs as well as through the local Champaign-Urbana community. Data from this project will provide a better understanding of the inflammatory response to different meals in healthy weight, overweight, and obese children.


Inclusion Criteria: • Between the ages of 7-17 Exclusion Criteria: - Younger than 7 years and older than 17 years - Presence of allergies to eggs and/or sugar substitutes - Presence of heart or respiratory disease - Presence of uncontrolled hypertension, diabetes - Use of anti-inflammatory medications - Presence of cancer or metabolic disease



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Urbana, Illinois 61801
United States

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Site Status: N/A

Data Source: ClinicalTrials.gov

Date Processed: June 24, 2021

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