Saint Louis, Missouri 63110


Purpose:

The objective of this prospective, observational study is to determine the association between the composition of the gut microbiota and the severity and persistence of Complex Regional Pain Syndrome symptoms (Study A). The objective of Study B, a longitudinal study of microbiota biomarkers of patients with newly diagnosed CRPS is to determine if the researchers can predict which patients are more likely to recover compared to those who do not. A secondary objective of both studies is to examine cognitive flexibility in relation to outcomes (study A and B).


Criteria:

Study A: Cross-sectional study Inclusion criteria, cases: - Adults over the age of 18 - Current (< 1 year duration) or former (> 1 year) diagnosis of Complex Regional Pain Syndrome by the Budapest criteria - English as primary language - able to consent Inclusion criteria, controls - Adults over age of 18 - Cohabitant of person with current or former diagnosis of CRPS Study B: Longitudinal Study Inclusion criteria, cases: - Adults over the age of 18 - Recent diagnosis (<6 months) of Complex Regional Pain Syndrome by the Budapest criteria - English as primary language - able to consent Inclusion criteria, controls - Adults over age of 18 - Cohabitant of person with diagnosis of CRPS Study A and B: Exclusion criteria, cases and controls: - Unwilling to participate in the study - Lives alone - Current use of probiotics and unwilling to stop for 1 week prior to stool sample - Pregnant or lactating - Vegan diet


NCT ID:

NCT03612193


Primary Contact:

Principal Investigator
Lara Crock, MD PhD
Washington University School of Medicine

Lara Crock, MD PhD
Phone: 314-546-3882
Email: crockl@wustl.edu


Backup Contact:

N/A


Location Contact:

Saint Louis, Missouri 63110
United States

Kristi Kraus, RN

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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