Iowa City, Iowa 52402


Purpose:

Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) has been established as an effective technique for sampling tissue inside and around the gastrointestinal tract, including the pancreas, liver, lymph nodes, and adrenal glands. EUS-FNA is convenient, minimally invasive, and safe procedure with an estimated sensitivity of 75%-92% and a specificity of 82%-100%. Diagnosis of various pathologies in the GI tract including solid pancreatic masses, mediastinal or gastric lymph nodes, gastrointestinal submucosal lesions, and peri-rectal lesions require adequate tissue architecture and immunohistochemical analysis. This is difficult to obtain and is frequently insufficient with EUS-FNA cytology alone. The core tissue is required to improve the diagnostic yield and obtain histologic diagnosis along with immunostaining to establish specimen adequacy. In past 1 year two new needle EUS needle (Shark Core)and Acquire EUS needles has been introduced to improve diagnostic accuracy, tissue yield, and potentially obtain a core tissue sample. So far, no prospective studies have compared these two needles to see which one is better for overall diagnostic accuracy. Our goal is to perform a prospective analysis to compare the diagnostic yield and safety profile of these 2 new EUS needle.


Criteria:

Inclusion Criteria: - Patients schedule for EUS guided biopsy Exclusion Criteria: - Patients who had EUS-FNA for cystic fluid aspiration - Pregnant females - International normalized ratio >1.5 and platelet count < 50,000 - Medically unstable


NCT ID:

NCT03672032


Primary Contact:

Henning Gerke, MD
Phone: 319-384-6582
Email: henning-gerke@uiowa.edu


Backup Contact:

Email: munish-ashat@uiowa.edu
Munish Ashat, MD
Phone: 319-353-4574


Location Contact:

Iowa City, Iowa 52402
United States

Henning Gerke, MD
Phone: 319-384-6582
Email: henning-gerke@uiowa.edu

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: February 04, 2019

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