Birmingham, Alabama 35294


Mobility refers to a person's purposeful movement through the environment from one place to another and can be conceptualized as a continuum from bed bound (immobility) on one extreme to making excursions to distant locations on the other extreme. Primary open-angle glaucoma (POAG) is a chronic, progressive optic neuropathy that can lead to gradual loss of vision in the peripheral field and central vision. Older adults with POAG have an increased risk for motor vehicle collisions and falls. Moreover, existing studies suggest that patients with POAG exhibit more postural sway while standing as measured by a balance platform and also tend to walk more slowly than those who are normally sighted and free of ocular disease. While these disturbances likely influence mobility, there has been little research directly assessing the impact of POAG on mobility. This study will assess the impact of POAG on life space (one aspect of mobility) and will determine whether difficulties with life space are associated with difficulties experienced under conditions of dim lighting.

Study summary:

Aim 1: To examine the extent of life space in older adults with POAG using the Life Space Questionnaire and to examine whether life space in persons with POAG is associated with the magnitude of visual field impairment. Aim 2: To examine difficulties seeing under dim illumination and at night in older adults with POAG using the Low Luminance Questionnaire and to examine whether greater difficulty in seeing under dim illumination and at night is related to the magnitude of visual field loss. Aim 3: To examine the relationship in older adults with POAG between visual problems seeing under dim illumination and at night (Low Luminance Questionnaire) and their life space (Life Space Questionnaire).


Inclusion Criteria: - Clinical diagnosis of primary open-angle glaucoma - Best-corrected visual acuity of 20/40 or better - Spherical refraction within ± 5 Diopters - Cylinder refraction within ± 3 Diopters Exclusion Criteria: - History of intra-ocular surgery other than uncomplicated cataract or glaucoma surgery - Significant cognitive impairment



Primary Contact:

Karen Searcey
Phone: 205-325-8310

Backup Contact:

Lindsay Gregg
Phone: 205-488-0777

Location Contact:

Birmingham, Alabama 35294
United States

Karen Searcey
Phone: 205-325-8616

Site Status: Recruiting

Data Source:

Date Processed: February 04, 2019

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