Seattle, Washington 98104

  • Depression

Purpose:

A double-blinded placebo-controlled randomized trial to evaluate the effect of preventative treatment of depression in survivors of aneurysmal subarachnoid hemorrhage (aSAH), a type of stroke.


Study summary:

Patients who suffered aneurysmal subarachnoid hemorrhage will be randomly assigned either an oral antidepressant or placebo and evaluated for the preventative treatment of depression and health-related quality-of-life.


Criteria:

Inclusion Criteria: Patients 18-85 years of age aged 18 years and older will be included. Patients admitted for subarachnoid hemorrhage from a ruptured cerebral aneurysm will be included. Only patients who provide informed consent will be included. Exclusion Criteria: Non-English speaking patients will be excluded. Patients currently receiving therapy for depression or related mental health diagnoses before admission will be excluded. Patients with medical contraindications to fluoxetine therapy will be excluded. Pregnant patients or patients considering pregnancy during the trial period at the time of consent will be excluded. Patients with active psychosis will be excluded. Patients who are incarcerated or in police custody will be excluded. Patients with a comorbidity or cognitive impairment (as determined by a recruiter-administered Montreal Cognitive Assessment; Patients scoring >26 are considered of appropriate cognitive function for consent) that precludes informed consent and participation in the research interviews will be excluded.


NCT ID:

NCT03826875


Primary Contact:

Principal Investigator
Michael Levitt, MD
University of Washington

Cory M Kelly
Phone: 206-685-3043
Email: kellycm@neurosurgery.washington.edu


Backup Contact:

N/A


Location Contact:

Seattle, Washington 98104
United States

Cory Kelly, BS
Phone: 206-685-3043

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: June 28, 2022

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