Philadelphia, Pennsylvania 19146


Purpose:

This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive mold infection (PIMI).


Criteria:

Inclusion Criteria: - Males or females age > 120 days and < 22 years at any participating site - Have at least one of the following conditions associated with a known high incidence of IMI: hematopoietic stem cell transplantation (HSCT), aplastic anemia, or hematologic malignancy - New (last 96 hours) radiographic evidence showing at least one pulmonary nodule ≥ 1 cm in diameter - Prolonged neutropenia (absolute neutrophil count < 500 cells/µl for a period of ≥ 5 consecutive days) in 30 days prior to qualifying chest MRI or CT scan date OR currently receiving systemic therapy for acute or chronic graft-versus-host disease (GVHD) on the date of the qualifying chest MRI or CT scan - Subject consent or parental/guardian permission (informed consent) and if appropriate, child assent Exclusion Criteria: - Weight <3 kg, so as to not exceed 3 ml/kg in a single blood draw - Previous inclusion in this study


NCT ID:

NCT03827694


Primary Contact:

Principal Investigator
William Steinbach
Duke University

PFN Central Coordinator
Phone: 919-668-4847
Email: PFNClinical@duke.edu


Backup Contact:

N/A


Location Contact:

Philadelphia, Pennsylvania 19146
United States



There is no listed contact information for this specific location.

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: October 09, 2019

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