Houston, Texas 77030


Purpose:

The main purpose of this study is to characterize the safety, tolerability, dose limiting toxicities, maximum tolerated dose, maximum administered dose, or alternative dose of BMS-986301 alone or in combination with nivolumab and ipilimumab to participants with cancers that have failed to respond to or are known to be insensitive to T cell checkpoint inhibiting antibodies.


Criteria:

For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: - Histologically or cytologically confirmed advanced/metastatic solid tumor and refractory to or intolerant of existing therapy(ies) known to provide clinical benefit for the condition of the participant - IO therapy resistant or insensitive tumors - Have at least 1 (intramuscular treatment group) or 2 (intratumoral treatment group) tumor lesions accessible for biopsy - Eastern Cooperative Oncology Group Performance Status of 0 or 1 Exclusion Criteria: - Primary central nervous system malignancy - Participants with other active malignancy requiring concurrent intervention - Uncontrolled or significant cardiovascular disease Other protocol defined inclusion/exclusion criteria could apply.


NCT ID:

NCT03956680


Primary Contact:

Recruiting sites have contact information. contact the sites directly.If there is no contact information.
Phone: Please email:
Email: Clinical.Trials@bms.com


Backup Contact:

First line of the email MUST contain NCT # and Site #


Location Contact:

Houston, Texas 77030
United States

Filip Janku, Site 0002
Phone: 713-745-4297

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: January 21, 2020

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