Columbia, Missouri 65212

  • Primary Total Knee Arthroplasty


To compare non-prescription sleep aids (low-dose diphenhydramine and melatonin) to sleep hygiene education for improving postoperative sleep quality after total joint arthroplasty.


Inclusion Criteria: All patients undergoing elective primary total hip or knee arthroplasty Exclusion Criteria: 1. History of substance abuse 2. Workman's compensation patients 3. Revision joint replacement 4. History of prescription or over-the- counter sleep aid use



Primary Contact:

Principal Investigator
James A Keeney, MD
University of Missouri Health System, Department of Orthopaedic Surgery

Stacee W Clawson, BSN, RN
Phone: 573-884-9017

Backup Contact:


Location Contact:

Columbia, Missouri 65212
United States

Susan Kady, BSN, RN

Site Status: Recruiting

Data Source:

Date Processed: August 03, 2021

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