Houston, Texas 77030

  • Hand Osteoarthritis

Purpose:

This is a study involving people receiving care at the Michael E. DeBakey VA Medical Center, Houston Texas. We are studying people who have hand osteoarthritis (the most common form of arthritis that involves the hand) and testing treatments for the condition with the hope that we can help to improve hand pain as well as limit the damage that occurs related to the arthritis. People who choose to participate, are randomly assigned to one of two treatments, both expected to be helpful.


Study summary:

The research will be conducted at the following location(s): Baylor College of Medicine, Baylor St. Luke's Medical Center (BSLMC), and Michael E. DeBakey Veterans Affairs Medical Center. Participants of this study are consented for the study, randomized into one of two treatment groups for hand osteoarthritis, both expected to improve hand symptoms. At the beginning of the study, many questionnaires, a physical exam, photographs of the hands, some x-rays, on a limited few people, and MRI will be obtained. Then the participants will be provided treatments for hand osteoarthritis based on the group wo which they were randomly assigned. One aspect of one of the treatments is viewed as experimental but the risks related to the treatment are considered to be low, so the risk-benefit ratio for participation in this study are good. We see patients in follow up more frequently during the first month, and then at 3 months and then 6 months of follow up. At the final visit, we will repeat the xrays and the MRIs.


Criteria:

Inclusion Criteria: - Enrolled to receive medical care at the Michael E. DeBakey VA Medical Center - At least 3 joints affected by distal interphalangeal (DIP) nodal hand OA - DIP nodal hand OA will be defined as Heberden's nodes on physical exam. - Sufficiently severe frequent pain of at least one DIP - Frequent pain: pain on most days of the month for at least one month in the last year. - Minimum VAS pain severity of 40 on a 0 - 100 scale Exclusion Criteria: - History or current inflammatory arthritides (examples: gout, psoriatic arthritis, and rheumatoid arthritis) - Prior surgery on the DIP joints - Planned surgery for the DIP joints - Pregnancy


NCT ID:

NCT04784065


Primary Contact:

Principal Investigator
Grace H Lo, MD MSc
Baylor College of Medicine

Grace H Lo, MD MSc
Phone: 713-791-1414 ext. 27804
Email: ghlo@bcm.edu


Backup Contact:

N/A


Location Contact:

Houston, Texas 77030
United States

Michael Strayhorn, MPH
Phone: 713-440-4646
Email: Michael.Strayhorn@va.gov

Site Status: Recruiting


Data Source: ClinicalTrials.gov

Date Processed: June 21, 2021

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